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1994-10-25
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Document 3056
DOCN M94A3056
TI Use of CD4 to predict outcome in HIV emergencies.
DT 9412
AU Chang R; Memorial Hospital, New York, NY 10021.
SO Int Conf AIDS. 1994 Aug 7-12;10(1):163 (abstract no. PB0080). Unique
Identifier : AIDSLINE ICA10/94369519
AB The CD4 count has been used as a marker for progression of HIV and
incorporated into staging and severity of illness scores for HIV, but
its usefulness as a prognostic marker in an acute setting has not been
explored. We investigated the use of CD4 in predicting hospitalization
in acutely ill HIV patients. A series of 210 visits by 97 HIV patients
to the emergency department of a tertiary care center was reviewed.
Using a multivariate model, we analyzed hospitalization as an outcome
variable as it related to the patients' age, sex, HIV risks, chief
complaints, acute physiologic derangements, and other relevant clinical
and laboratory findings (15 variables). We found the CD4 count to be
independently significant (p = .016) in predicting acute HIV
hospitalization. Of 210 visits, the mean CD4 of hospitalized patients
was 71 (range 2-361) compared to the mean CD4 of 123 (range 2-659) for
discharged patients. Of 12 patients with CD4 greater than 400, none were
hospitalized. Our preliminary data indicates that the CD4 count is
independently useful as a prognostic marker for the need for
hospitalization in acutely ill HIV patients. We suggest that an HIV
patient's CD4 count be incorporated in the decision making regarding
disposition in an acute setting.
DE Antigens, CD4/*BLOOD *Emergencies Human HIV
Infections/CLASSIFICATION/DIAGNOSIS/*IMMUNOLOGY *Leukocyte Count
*Patient Admission Prognosis Risk Factors T4 Lymphocytes/*IMMUNOLOGY
MEETING ABSTRACT
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).